A 22-year-old female with a solitary 1 cm rubbery, well-circumscribed, non-tender breast mass: Most likely diagnosis?

• A. Fibroadenoma
• B. Breast fat necrosis
• C. Fibrocystic changes
• D. Intraductal papilloma

Answer: (A)

A solitary, small, rubbery, well-defined, non-tender breast mass in a young woman is classic for a fibroadenoma. Fibroadenomas are benign tumors made of fibrous and glandular tissue and tend to be mobile with smooth, well-circumscribed margins. They commonly arise in adolescents and young adults and are often about 1 cm in size, though they can grow larger. This pattern differs from fat necrosis, which usually follows trauma and may appear irregular with skin or fat changes; fibrocystic changes typically produce multiple, bilateral, often tender lumps that fluctuate with the menstrual cycle; and intraductal papilloma usually presents near the nipple with possible discharge rather than a discrete breast lump. So the described features fit a fibroadenoma best.