Anti-phospholipid antibodies are present in approximately what percentage of SLE patients?

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Multiple Choice

Anti-phospholipid antibodies are present in approximately what percentage of SLE patients?

Explanation:
Antiphospholipid antibodies appear fairly commonly in systemic lupus erythematosus, though not in all patients. These antibodies—lupus anticoagulant, anticardiolipin, and anti-beta2 glycoprotein I—are detected in about one quarter of SLE patients at some point. That makes the roughly 25% figure the best estimate for prevalence. Clinically, their presence matters because it increases the risk of thrombosis and pregnancy-related complications, and can cause paradoxical prolongation of certain clotting tests in vitro even though bleeding risk isn’t the primary concern. The other percentages (10%, 50%, 75%) don’t align with how commonly these antibodies are found in SLE.

Antiphospholipid antibodies appear fairly commonly in systemic lupus erythematosus, though not in all patients. These antibodies—lupus anticoagulant, anticardiolipin, and anti-beta2 glycoprotein I—are detected in about one quarter of SLE patients at some point. That makes the roughly 25% figure the best estimate for prevalence. Clinically, their presence matters because it increases the risk of thrombosis and pregnancy-related complications, and can cause paradoxical prolongation of certain clotting tests in vitro even though bleeding risk isn’t the primary concern. The other percentages (10%, 50%, 75%) don’t align with how commonly these antibodies are found in SLE.

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