Ceftriaxone is commonly used to treat which condition?

• A. Gonorrhea
• B. Trichomonas vaginitis
• C. Genital herpes
• D. Syphilis

Answer: (A)

Ceftriaxone is a third-generation cephalosporin with strong activity against Neisseria gonorrhoeae and excellent tissue penetration, including the urogenital tract. Because gonorrhoeae has developed resistance to many older antibiotics, ceftriaxone remains a reliable first-line choice, usually given as an intramuscular dose and often paired with treatment for possible chlamydial coinfection. The other conditions are caused by different pathogens and require different therapies: Trichomonas vaginitis is treated with metronidazole, genital herpes with antiviral agents like acyclovir, and syphilis with penicillin G (with ceftriaxone as an alternative only in certain penicillin-allergic cases, not the standard first-line). Therefore, ceftriaxone is most commonly used to treat gonorrhea.