Diphenoxylate (Lomotil) is used to treat which condition?

Enhance your readiness for the Physician Assistant Clinical Knowledge Rating and Assessment Tool (PACKRAT) 4 Exam. Utilize our flashcards and multiple-choice questions, complete with hints and explanations, to ace your upcoming test!

Multiple Choice

Diphenoxylate (Lomotil) is used to treat which condition?

Explanation:
Diphenoxylate treats diarrhea by slowing intestinal motility. It is an opioid receptor agonist in the gut, which reduces propulsive peristalsis and allows more water to be absorbed from the stool, decreasing stool frequency and liquidity. It’s often combined with a small amount of atropine to discourage abuse. It’s not used for inflammatory bowel disease, nausea, or NSAID-induced ulcers, which require different treatments. Diphenoxylate is more suited to nonspecific acute or chronic diarrhea rather than conditions involving mucosal inflammation or ulcers.

Diphenoxylate treats diarrhea by slowing intestinal motility. It is an opioid receptor agonist in the gut, which reduces propulsive peristalsis and allows more water to be absorbed from the stool, decreasing stool frequency and liquidity. It’s often combined with a small amount of atropine to discourage abuse. It’s not used for inflammatory bowel disease, nausea, or NSAID-induced ulcers, which require different treatments. Diphenoxylate is more suited to nonspecific acute or chronic diarrhea rather than conditions involving mucosal inflammation or ulcers.

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