Infectious mononucleosis caused by EBV, which treatment is most appropriate?

Enhance your readiness for the Physician Assistant Clinical Knowledge Rating and Assessment Tool (PACKRAT) 4 Exam. Utilize our flashcards and multiple-choice questions, complete with hints and explanations, to ace your upcoming test!

Multiple Choice

Infectious mononucleosis caused by EBV, which treatment is most appropriate?

Explanation:
Infectious mononucleosis from EBV is a viral illness, so treatment focuses on symptom relief rather than eradicating the virus. Acetaminophen is the best choice because it provides fever reduction and helps with throat discomfort and aches, which are common symptoms in mono. There isn’t a proven antiviral therapy that shortens illness for EBV, and antibiotics don’t treat viral infections. If there’s no bacterial infection, antibiotics aren’t indicated. Acyclovir has not shown meaningful benefit for uncomplicated mono. In addition to symptomatic care, patients are often advised to rest and stay hydrated, and to avoid heavy lifting or contact sports for several weeks due to the risk of splenomegaly.

Infectious mononucleosis from EBV is a viral illness, so treatment focuses on symptom relief rather than eradicating the virus. Acetaminophen is the best choice because it provides fever reduction and helps with throat discomfort and aches, which are common symptoms in mono. There isn’t a proven antiviral therapy that shortens illness for EBV, and antibiotics don’t treat viral infections. If there’s no bacterial infection, antibiotics aren’t indicated. Acyclovir has not shown meaningful benefit for uncomplicated mono. In addition to symptomatic care, patients are often advised to rest and stay hydrated, and to avoid heavy lifting or contact sports for several weeks due to the risk of splenomegaly.

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